Sappire S-Tox Complex of Growth Factors and Vitamins. 16 Cell Growth Factors & Antioxidant vitamins. Sappire S-Tox cantains 16 ingredients necessary for cell growth factor and promotion of collagen and elastin, reducing wrinkles and maintaining elasticity. Removes active oxygen and prevents skin aging through antioxidant vitamins In additon, Sappire contains anti-pigmentation and whitening properties, as well as antibacterial and moisturizing properties. This is ideal for evening application, on a clean skin surface , topically or via microneedle/dermaroller treatment.